Multiscale modeling and simulations to bridge molecular and cellular scales

Stochastic Immunology

speaker: Grant Lythe (Applied Mathematics, Leeds)

abstract: An important part of the body's immune response is the encounter between T cells and antigen- presenting cells inside lymph nodes, where their motion appears to be random. I will discuss ways to estimate timescales under the simplest hypothesis, that cell motion is Brownian. I will also consider homeostasis: a repertoire of T cells of many dierent specicities is maintained over many years because death of cells is balanced by a combination of cell division and new cells from the thymus. Our knowledge is based on estimates and extrapolation from small samples.

timetable:
Thu 4 Oct, 11:00 - 12:15, Aula Dini
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