abstract: We prove that the defocusing quintic wave equation, with Dirichlet boundary conditions, is globally well posed on $H10(\Omega) \times L2( \Omega)$ for any smooth (compact) domain $\Omega \subset \mathbb{R}3$. The main ingredient in the proof is an $L5$ spectral projector estimate, obtained recently by Smith and Sogge, combined with a detailed study of the boundary value problem.